Table 2.
Author (Year) | Country | Age | Sex | Chronic illness | Symptoms | Bilateral patchy groundglass opacities due to COVID-19 | Mechanical ventilation | TCZ dosing | Death | Recovered |
---|---|---|---|---|---|---|---|---|---|---|
Ferrey (2020) | United States | 56 | M | ESRD, CAD, CMOP | Cough, fever, N/V, SOB, diarrhea, myalgias, afib, ARDS | Yes | Yes | NR | No | Unknown |
Michot (2020) | France | 42 | M | mCCRCC | Cough, fever, SOB | Yes | No | 8 mg/kg IV x 2 doses | No | Yes |
Mihai (2020) | Switzerland | 57 | F | SSc-ILD, T2DM, obesity | Cough, headache, malaise | No | No | 8 mg/kg IV every 4 weeks x 3 years | No | Yes |
Zhang (2020) | China | 60 | M | MM | Chest tightness, SOB | Yes | No | 8 mg/kg IV x 1 dose | No | Yes |
Abbreviations: afib: atrial fibrillation; ARDS: acute respiratory distress syndrome; CAD: coronary artery disease; CMOP: cardiomyopathy; ESRD: end-stage renal disease; F: female; IV: intravenous; N/V: nausea and vomiting; NR: not reported; M: male; mCCRCC: metastatic clear cell renal cell carcinoma; MM: multiple myeloma; SOB: shortness of breath; SSc-ILD: systemic sclerosis with interstitial lung disease; T2DM: type II diabetes mellitus; TCZ: tocilizumab.