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. 2020 Apr 21;127:104380. doi: 10.1016/j.jcv.2020.104380

Table 2.

Case reports involving the use of tocilizumab in patients with COVID-19.

Author (Year) Country Age Sex Chronic illness Symptoms Bilateral patchy groundglass opacities due to COVID-19 Mechanical ventilation TCZ dosing Death Recovered
Ferrey (2020) United States 56 M ESRD, CAD, CMOP Cough, fever, N/V, SOB, diarrhea, myalgias, afib, ARDS Yes Yes NR No Unknown
Michot (2020) France 42 M mCCRCC Cough, fever, SOB Yes No 8 mg/kg IV x 2 doses No Yes
Mihai (2020) Switzerland 57 F SSc-ILD, T2DM, obesity Cough, headache, malaise No No 8 mg/kg IV every 4 weeks x 3 years No Yes
Zhang (2020) China 60 M MM Chest tightness, SOB Yes No 8 mg/kg IV x 1 dose No Yes

Abbreviations: afib: atrial fibrillation; ARDS: acute respiratory distress syndrome; CAD: coronary artery disease; CMOP: cardiomyopathy; ESRD: end-stage renal disease; F: female; IV: intravenous; N/V: nausea and vomiting; NR: not reported; M: male; mCCRCC: metastatic clear cell renal cell carcinoma; MM: multiple myeloma; SOB: shortness of breath; SSc-ILD: systemic sclerosis with interstitial lung disease; T2DM: type II diabetes mellitus; TCZ: tocilizumab.