Baseline T2 lesion volume vs. EDSS score at baseline and 5-year follow-up
Global cerebral T2 hyperintense lesion volume (T2LV) at baseline vs. Expanded Disability Status Scale (EDSS) score at baseline and at 5-year follow-up from the Brigham and Women’s Hospital (BWH) (top) and the University of California, San Francisco (UCSF) (bottom) cohorts. Scatter plots with regression slopes illustrate the relationship between T2LV and EDSS score at baseline (BWH: Pearson r = 0.178, p=0.077, UCSF: r = 0.207, p=0.038), and at 5-year follow-up (BWH: Pearson r = 0.237, p=0.017, UCSF: r = 0.294, p=0.003). The correlation coefficients were not different between the two cohorts at either time point (p>0.05). See also Table 2.