Table 1.

List of antiviral agents docked against COVID-19 [27].

No	Name	Structure	Active against	Mechanism
1	ABT450		Hepatitis C	Inhibitor of the non-structural protein 3-4A (NS3/4A) serine protease
2	Acyclovir		Cytomegalovirus infections	Inhibits viral DNA polymerase
3	Amprenavir		HIV	Protease inhibitor
4	Arbidol (Umifenovir)		Influenza	Inhibits membrane fusion
5	Adefovir		HIV	Reverse transcriptase inhibitor
6	Azidothimidine		HIV	Inhibits reverse transcriptase
7	Asunaprevir		Hepatitis C	Protease inhibitor
8	Baricitinib		Rheumatoid arthritis	Inhibits Janus kinase
9	Beclabuvir		Hepatitis C	Inhibits non-structural protein 5B (NS5B)
10	Boceprevir		Hepatitis C	NS3/4A protease inhibitor
11	Brivudin		Herpes zoster	Blocks the action of DNA polymerases
12	Camostate		Pancreatitis	Inhibits serine protease
13	Darunavir		HIV	Inhibits HIV protease enzyme
14	Delavirdine		HIV	Non-nucleoside reverse transcriptase inhibitor
15	Didanosine		HIV	Nucleoside reverse transcriptase inhibitor
16	CGP42112A		Vasodilation and blood pressure reduction	Angiotensin AT2 receptor agonist
17	Dasabuvir		Hepatitis C	Inhibits the action of NS5B polymerase
18	Danoprevir		Hepatitis C	NS3/4A protease inhibitor
19	Daclatasvir		Hepatitis C	NS5A inhibitor
20	Elvitegravir		HIV	Integrase inhibitor
21	Favipiravir		Influenza	Inhibits viral RNA-dependent RNA polymerase (RdRp)
22	Dihydroxy propyladenine		Herpes Virus	Inhibits viral replication
23	Efavirenz		HIV	Inhibits non-nucleoside reverse transcriptase enzyme
24	Faldaprevir		Hepatitis C	Protease inhibitor
25	Famciclovir		Hepatitis B	Inhibits viral DNA polymerase
26	Galidesivir		Ebola	RNA polymerase inhibitor
27	Entecavir		Hepatitis B	Inhibits reverse transcription
28	Elbasvir		Hepatitis C	NS5A inhibitor
29	Ganciclovir		Cytomegalovirus	Inhibits viral DNA polymerases
30	Grazoprevir		Hepatitis C	Blocks NS3
31	Iodoxuridine		Herpes Simplex virus	Interferes viral DNA replication
32	Ritonavir		HIV	HIV protease inhibitor
33	Indinavir		HIV	Protease inhibitor
34	Maraviroc		HIV	Negative allosteric modulator of the C—C chemokine receptor type 5
35	Marboran/Methisazone		Small pox virus	Inhibits mRNA and protein synthesis
36	Lopinavir		HIV	Protease inhibitor
37	Mericitabine		Hepatitis C	Inhibitor of RdRp
38	Nitrazoxanide		Broad-spectrum antiviral	Pyruvate:ferredoxin oxidoreductase (PFOR) enzyme
39	Radalbuvir		Hepatitis C	NS5B inhibitor
40	Remdesivir		Ebola virus, Respiratory syncytial virus	Viral RNA polymerase
41	Raltegravir		HIV	HIV-1 integrase inhibitor
42	Nevirapine		HIV	Non-nucleoside reverse transcriptase inhibitor
43	Foscarnet		Herpes viruses, HIV, and hepatitis B virus	Inhibits the pyrophosphate binding site on viral DNA polymerases
44	Sequinavir		HIV	Protease inhibitor
45	NSC306711 (Ferristatin II)		Flavivirus	Degradation of Transferrin receptor- 1
46	Amantadine		Influenza A	Antagonism of the influenza virus A-M2 proton channel
47	Simeprevir		Hepatitis C	Hepatitis C virus protease inhibitor
48	Ombitasvir		Hepatitis C	NS5A inhibitor
49	Sofosbuvir		Hepatitis C	Inhibitor of viral RNA synthesis by inhibiting NS5B protein
50	Stavudine		HIV	Inhibits HIV reverse transcriptase enzyme
51	Zanamivir		Influenza viruses	Neuraminidase inhibitor
52	Telbivudine		Hepatitis B	Reverse transcriptase inhibitor
53	Ravidasvir		Hepatitis C	NS5A inhibitor
54	Zalcitabine		HIV	Nucleoside reverse transcriptase inhibitor
55	Tenofovir		HIV	Inhibits the activity of HIV-1 reverse transcriptase
56	Telaprevir		Hepatitis C	NS3/4a protease inhibitor
57	Velpatsvir		Hepatitis C	NS5A protein inhibitor
58	Vedroprevir		Hepatitis C	Inhibitor of the Hepatitis C virus (HCV) NS3
59	Vaniprevir		Hepatitis C	NS3/4A protease inhibitor
60	Uprifosbuvir		Hepatitis C	NS5B polymerase inhibitor
61	Oseltamivir		Influenza viruses A	Inhibits the neuraminidase enzyme