Table 3.
Clinical features of the study patients and according to disease severity. IQR = inter quartile range. Numerals in parenthesis represent percentages or IQR. Table modified from Table 1, illustrated in original article. Guan W et al. N Engl J Med. February 28, 2020. https://doi.org/10.1056/NEJMoa2002032.
| Characteristic | All patients | Non-severe disease | Severe disease |
|---|---|---|---|
| Age - median (IQR) years |
47 (35–58) |
45 (54–57) |
52 (40–65) |
|
Distribution |
no./total no. (%) |
||
| 0–14 yr | 9/1011 (0.9) | 8/848 (0.9) | 1/163 (0.6) |
| 15–49 yr | 557/1011 (55.1) | 490/848 (57.8) | 67/163 (41.1) |
| 50–64 yr | 292/1011 (28.9) | 241/848 (28.4) | 51/163 (31.3) |
| >65 yr | 153/1011 (15.1) | 109/848 (12.9) | 44/163 (27) |
| Females |
459/1096 (41.9) |
386/923 (41.8) |
73/173 (42.2) |
| Median incubation period days (IQR) |
4 (2–7) |
4 (2.8–7.0) |
4 (2.0–7.0) |
| Patients with fever | 473/1081 (43.8) | 391/910 (43) | 82/171 (48) |
| Symptom No. (%) | |||
| Conjunctiva cong. | 9 (0.8) | 5 (0.5) | 4 (2.3) |
| Nasal congestion | 53 (4.8) | 47 (5.1) | 6 (3.5) |
| Headache | 150 (13.6) | 124 (13.4) | 26 (15) |
| Cough | 745 (67.8) | 623 (67.3) | 122 (70.5) |
| Sore throat | 153 (13.9) | 130 (14) | 23 (13.3) |
| Sputum product | 370 (33.7) | 309 (33.4) | 61 (31.3) |
| Fatigue | 419 (38.1) | 350 (37.8) | 69 (39.9) |
| Hemoptysis | 10 (0.9) | 6 (0.6) | 4 (2.3) |
| Breathlessness | 205 (18.7) | 140 (15.1) | 65 (37.6) |
| Nausea/vomiting | 55 (5) | 43 (4.6) | 12 (6.9) |
| Diarrhea | 42 (3.8) | 32 (3.5) | 10 (5.8) |
| Myalgias/arthralgia | 164 (14.9) | 134 (14.5) | 30 (17.3) |
| Chills | 126 (11.5) | 100 (10.8) | 26 (15) |
| Signs of infection | |||
| Throat congestion | 19 (1.7) | 17 (1.8) | 2 (1.2) |
| Tonsils enlarged | 23 (2.1) | 17 (1.8) | 6 (3.5) |
| Lymphadenopathy | 2 (0.2) | 1 (0.1) | 1 (0.6) |
| Rash | 2 (0.2) | 0 | 2 (1.2) |
| Coexisting disorder | 261 (23.7) | 194 (21) | 67 (38.7) |