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. 2020 Apr 3;159(1):81–95. doi: 10.1053/j.gastro.2020.03.065

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© 2020 by the AGA Institute.

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Study selection flow diagram. If all gastrointestinal symptoms were not reported and the number of events of any individual gastrointestinal symptom was >1, it was regarded as not available and was excluded from the meta-analysis of all gastrointestinal symptoms. However, the study was still included in the meta-analysis of individual gastrointestinal symptom if the proportion of patients with that symptom was reported.