Table 3.
Laboratory findings and etiologies of encephalitis in 241 adult patients with encephalitis.
| Laboratory findings | N (%) |
|---|---|
| Serum WBC, median, (range)a | 6500 (1300−43500) |
| Serum glucose, median, mg/dl, (range) | 110 (59−609) |
| CSF WBC, median, cells/mm3, (range) | 30 (0−2500) |
| CSF lymphocyte percent (range) | 83 (0−100) |
| CSF protein, median, mg/dl, (range) | 76 (19−939) |
| CSF glucose, median, mg/dl, (range) | 60 (1−253) |
| Leukopeniab | 18 (7.5) |
| Thrombocytopeniac | 34 (14.1) |
| Etiologies | |
| Idiopathic | 101 (41.9) |
| Virald | 67 (27.8) |
| Autoimmunee | 51 (21.2) |
| Bacterialf | 15 (6.2) |
| Parasiticg | 4 (1.7) |
| Fungalh | 3 (1.2) |
Abbreviations: WBC, white blood cells; mg/dl, milligram per deciliter; mm3, per cubic millimeter; WNV, west nile virus; HSV, herpes simplex virus; VZV, varicella zoster virus; CMV, cytomegalovirus; NMDA, N-methyl-d-aspartate; VGKC, voltage - gated potassium channel; TB, tuberculosis.
Number of white blood count per microliter.
White blood count less than 4000 per microliter.
Platelets count less than 150 per microliter.
The distribution of causative viruses was as it follows: WNV (28), HSV (22), VZV (11), CMV (4) and Enterovirus (2).
They were due to anti-NMDA (21), anti-VGKC (2) and the rest were due to other autoimmune diseases: Systemic lupus erythematosus (n=18), Sarcoidosis (n=7), Hashimoto's disease (n=2) and Rheumatoid arthritis (n=1).
Bacterial causes were due to Mycobacterium tuberculosis (4), Group A streptococcus (3), Streptococcus pneumoniae (2), Syphilis (2), Rickettsia spp (1), Brucella (1), Staphylococcus aureus (2).
Toxoplasma gondii (n=4).
Fungal etiologies include Cryptococcus neoformans (n=2) and Coccidioides immitis (n=1).