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. Author manuscript; available in PMC: 2020 Sep 26.
Published in final edited form as: Nat Microbiol. 2020 Mar 26;5(4):620–629. doi: 10.1038/s41564-020-0692-2

Extended Data Fig. 2. Anti-CRISPR distribution in integrative mobile genetic elements across bacterial taxa.

Extended Data Fig. 2

Phylogenetic analysis based on acrIIA16–19 homologs (panels a to d, respectively) reconstructed from a midpoint rooted minimum-evolution of full-length protein sequences identified following an iterative PSI-BLASTp search, see methods for details. Number of genomes included to construct each tree for acrIIA16-19 are seventy, twenty-six, eighty-four and seventeen respectively. Branches are labeled with species name and colored according to species class (see legend). Species for which AcrIIA homologs have been tested in this study are shown in bold.