Table II.

Summary of advantages and limitations of phototherapy and biologics

	Phototherapy	Biologics
Advantages	Effective Rapid acting (targeted phototherapy) Known long-term safety record No laboratory monitoring needed Safe for children and pregnant and nursing mothers (NB-UVB) Lower cost	Highly effective (takes 8-12 weeks) Immune modulators Good short-term safety record Convenient to administer
Limitations	Availability and access Necessitates equipment, staff, and space Requires patient's time and effort Involves thorough patient education (for home phototherapy)	Expensive cost Requires laboratory testing and monitoring Lacking long-term safety data