Table 2.
Clinical Laboratory Trends in Patient 2
| Laboratory Value | D1 | D2a | D3 | D4a | D5 | D6 | D7 |
|---|---|---|---|---|---|---|---|
| WBC count, × 103/μL | 2.1 | 3.6 | 2.6 | 1.5 | 1.6 | 2.2 | 5.3 |
| Platelet count, × 103/μL | 397 | 286 | 329 | 102 | 60 | 45 | 26 |
| Neutrophil count, × 103/μL | 0.6 | 0.8 | 1.2 | … | … | 1.1 | 2.3 |
| Lymphocyte count, × 103/μL | 1.0 | 2.4 | 0.6 | … | … | 0.3 | 0.3 |
| NLR | 0.6 | 0.3 | 0.5 | … | 3.7 | 7.7 | |
| Fibrinogen, mg/dL | … | … | … | … | 183 | 104 | 35 |
| D-dimer, ng/mL | 830 | … | 5,964 | … | 60,983 | 87,206 | 67,094 |
| Creatinine, mg/dL | 0.9 | 1.5 | 2.9 | 3.7 | 2.6b | 1.1b | 0.9b |
| Alanine aminotransferase, IU/L | 154 | 99 | 66 | 161 | 1,438 | 1,316 | 932 |
| Aspartate aminotransferase, IU/L | 254 | 131 | 97 | 837 | > 7,000 | 4,432 | 2,963 |
| Ferritin, ng/mL | 2,052 | … | … | … | 33,315 | 63,378 | 40,934 |
| Lactate dehydrogenase, IU/L | … | … | … | … | … | … | … |
| C-reactive protein, mg/dL | … | 20.8 | … | 33.0 | 20.4 | 12.6 | 8.4 |
| IL-6, pg/mL | … | … | > 400 | … | … | … | … |
| Triglycerides, mg/dL | … | … | … | … | … | … | … |
| Troponin T, ng/mL | < 0.01 | … | … | … | … | 0.03 | 0.04 |
See Table 1 legend for expansion of abbreviations.
a
Tocilizumab administered on days 2 and 4.
b
Value obtained after initiation of dialysis.