Comparison 8. All fish oil containing LE versus S‐LE.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
8.1 Death before discharge	5	399	Risk Ratio (M‐H, Fixed, 95% CI)	1.28 [0.69, 2.35]
8.2 Days to regain birth weight	3	261	Mean Difference (IV, Fixed, 95% CI)	0.81 [‐0.43, 2.05]
8.3 Rate of weight gain (g/kg/day)	5	374	Mean Difference (IV, Fixed, 95% CI)	0.69 [‐0.19, 1.57]
8.4 Bronchopulmonary dysplasia/chronic lung disease	4	341	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.70, 1.50]
8.5 Duration of ventilation (days)	3	208	Mean Difference (IV, Fixed, 95% CI)	‐0.59 [‐3.79, 2.60]
8.6 Duration of supplemental oxygen (days)	2	140	Mean Difference (IV, Fixed, 95% CI)	0.47 [‐2.01, 2.95]
8.7 Culture positive sepsis	1	80	Risk Ratio (M‐H, Fixed, 95% CI)	0.67 [0.12, 3.78]
8.8 Any sepsis (clinical and/or culture positive)	5	373	Risk Ratio (M‐H, Fixed, 95% CI)	0.92 [0.61, 1.39]
8.9 Necrotising enterocolitis (≥ stage 2)	4	341	Risk Ratio (M‐H, Fixed, 95% CI)	1.29 [0.65, 2.57]
8.10 Duration of phototherapy (days)	1	32	Mean Difference (IV, Fixed, 95% CI)	0.00 [‐2.57, 2.57]
8.11 Retinopathy of prematurity (≥ stage 3)	3	256	Risk Ratio (M‐H, Fixed, 95% CI)	0.43 [0.06, 2.85]
8.12 Intraventricular haemorrhage (grade III‐IV)	3	256	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.51, 2.04]
8.13 Periventricular leukomalacia	2	176	Risk Difference (M‐H, Fixed, 95% CI)	0.00 [‐0.03, 0.03]
8.14 Any patent ductus arteriosus	3	261	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.72, 1.21]
8.15 Significant patent ductus arteriosus requiring treatment	1	96	Risk Ratio (M‐H, Fixed, 95% CI)	0.83 [0.52, 1.31]
8.16 Parenteral nutrition associated liver disease/cholestasis	4	341	Risk Ratio (M‐H, Fixed, 95% CI)	0.80 [0.29, 2.16]
8.17 Hypertriglyceridaemia	1	96	Risk Ratio (M‐H, Fixed, 95% CI)	1.00 [0.61, 1.64]
8.18 Hyperglycaemia	2	112	Risk Ratio (M‐H, Fixed, 95% CI)	0.92 [0.27, 3.11]
8.19 Hypoglycaemia	1	80	Risk Ratio (M‐H, Fixed, 95% CI)	0.14 [0.01, 2.68]