| Study | Reason for exclusion |
|---|---|
| Angsten 2002 | The study included term infants. Population included 36 to 41 week newborns ≤ 4 days of age needing surgery and expected to require total parenteral nutrition for at least 5 days. |
| Ariyawangso | The study included newborns requiring surgery and included term infants. Infants were randomised to receive SMOFlipid® 20% (experimental group, n = 21) or Intralipid® 20% (control group, n = 21). |
| Lam 2014 | Infants with parenteral nutrition‐associated cholestasis (conjugated bilirubin concentration ≥ 34 µmol/l or 2 mg/dl) and expected to be parenteral nutrition‐dependent for > 2 weeks were randomised to receive either fish oil based lipid preparation or soy oil based lipid preparation at 1.5 g/kg/day. |
| Lima 1988 | The study included term infants up to 38 weeks gestation. |
| Magnusson 1997 | The population included newborn infants requiring surgery and included term infants. |
| Nehra 2014 | Inclusion criteria included newborn and infants < 3 months with gastrointestinal disease requiring surgery (included term infants). Fish oil LE (Omegaven®; n=9) versus soy LE (Intraplipid®; n=10). |
| Webb 2008 | The study included term babies with mean gestation of infants 37.0 ± 3.6 and 36.7± 3.0 weeks in the two arms of the study. |
| Wilson 1997 | This study aimed to compare "aggressive parenteral nutrition" in preterm infants versus "conventional parenteral nutrition." The "aggressive nutrition group" received a higher rate of lipids, proteins, dextrose and 33% of participants in this group received insulin besides getting medium chain and long chain triglyceride based LE (Lipofundin®). The conventional nutrition group received a lesser percentage of dextrose, lesser rate of lipids (S‐LE) and no insulin. The duration of LE was a median of 20 days (interquartile range 12‐28 days) in the aggressive nutrition (MS‐LE) group versus a median of 6 days (interquartile range 2‐15 days) in the conventional nutrition (S‐LE group). This study, done in 1997, reported advantages of the aggressive parenteral nutritional regimen versus conventional parenteral nutrition. |
LE: lipid emulsion