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. Author manuscript; available in PMC: 2020 Oct 13.
Published in final edited form as: Nat Neurosci. 2020 Apr 13;23(5):638–650. doi: 10.1038/s41593-020-0617-7

Figure 7: Knockdown of OxR2 in GAD2 LHb modulates aggressive behavior in AGGs.

Figure 7:

a, Surgical manipulations for GAD2 neuron-specific knockdown of OxR2 in the LHb. b, Representative viral infection for GAD2 neuron-specific knockdown of OxR2 in the LHb, scale bar=300 μm. c, OxR2 knockdown in GAD2 LHb neurons increased attack latency in RI (two-tailed student’s t-test, n=12 biologically independent mice per group, t(22)=2.322, p=0.0299). d, OxR2 knockdown in GAD2 LHb neurons reduced attack duration in RI (two-tailed student’s t-test, n=12 biologically independent mice per group, t(22)=3.183, p=0.0043). e, OxR2 knockdown in GAD2 LHb neurons reduced aggression CPP (two-tailed student’s t-test, n=12 biologically independent mice per group, t(22)=2.155, p=0,0424). * p<0.05, **p<0.01. All data are expressed as mean ± SEM.