Table 2.

Prevalence of psychiatric medication use during the five years before, 1 year after and fifth year after the first hospitalization with schizophrenia-spectrum diagnosis (SSD) for women (n = 7142) and men (n = 9006).

	Medication use during 5 years before SSD				Medication use during first five years after SSD
	Women (%)	Men (%)	p-value	OR (95% CI) for women	Women (%)	Men (%)	p-value	OR (95% CI) for women
Antipsychotics	77.6	71.7	<0.0001	1.37 (1.28–1.47)	96.6	94.4	<0.0001	1.7 (1.46–2.0)
Antidepressants	58.6	50.6	<0.0001	1.38 (1.3–1.47)	60.0	52.5	<0.0001	1.36 (1.27–1.45)
SSRIs	47.8	39.8	<0.0001	1.38 (1.3–1.47)	45.7	37.7	<0.0001	1.39 (1.31–1.48)
Other antidepressants	28.8	26.2	<0.0001	1.2 (1.12–1.29)	33.3	29.5	<0.0001	1.2 (1.12–1.28)
Benzodiazepines	48.2	41.2	<0.0001	1.3 (1.21–1.38)	53.1	45.2	<0.0001	1.37 (1.29–1.46)
Mood stabilizers	20.1	14.9	<0.0001	1.44 (1.33–1.56)	33.1	26.1	<0.0001	1.4 (1.31–1.5)
Zopiclone and zolpidem	22.9	17.6	<0.0001	1.39 (1.28–1.5)	26.2	19.8	<0.0001	1.43 (1.33–1.54)
ADHD medication	0.4	0.9	<0.0001	0.37 (0.24–0.58)	0.3	0.8	<0.0001	0.35 (0.21–0.56)
Specific antipsychotics
Clozapine	5.0	4.1	0.0063	1.23 (1.06–1.43)	26.9	31.4	<0.0001	0.8 (0.75–0.86)
Olanzapine	27.8	29.0	0.1017	0.94 (0.88–1.0)	43.5	45.8	0.0027	0.91 (0.85–0.97)
Quetiapine	29.3	21.9	<0.0001	1.48 (1.38–1.59)	45.1	35.7	<0.0001	1.48 (1.39–1.58)
Risperidone	33.6	32.7	0.2269	1.04 (0.98–1.1)	29.3	29.6	0.7151	0.99 (0.92–1.1)
Aripiprazole	9.5	7.8	0.0001	1.24 (1.11–1.39)	25.3	23.2	0.0031	1.12 (1.04–1.2)
Any long-acting antipsychotics	7.0	6.1	0.0258	1.15 (1.02–1.31)	20.1	22.1	0.0017	0.89 (0.82–0.96)

ADHD medication is mostly methylphenidate.