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. 2020 May 1;11:2150. doi: 10.1038/s41467-020-16044-8

Fig. 4. Localization of miR669f-3p, Sfmbt2 miRNA, in E11.5 placenta.

Fig. 4

a In situ hybridization image of a normal (IVF-derived) placenta at E11.5. The areas corresponding to the magnified images in b and c are indicated by black squares. ST spongiotrophoblast layer, LB labyrinthine layer. Scale bar, 1 mm. b–e In situ hybridization using probes for miR669f-3p and negative-control probes. The nuclei in the cell layer of secondary trophoblast giant cells (TG) were clearly stained for miR669f-3p b. The nuclei of trophoblasts in the ST layer and immature trophoblasts in the LB layer d were also clearly stained. Their cytoplasm was faintly stained. Scale bar, 100 μm.