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. 2020 May 1;11:2165. doi: 10.1038/s41467-020-15982-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Direct visualization of ZsGreen-labeled ERα neurons in a coronal hypothalamic section from a female ERα-ZsGreen mouse. The VMH subdivisions, dmVMH, cVMH, and vlVMH, were highlighted with white borders. The similar results were replicated three times. b Percentage of glucose-sensing or non-glucose-sensing neurons in different VMH subgroups. c Percentage of GI and GE neurons within the ERα^vlVMH population in gonad-intact female mice. d, e Representative electrophysiological responses to glucose fluctuations (5→1→5 mM) in a GI d and a GE-ERα^vlVMH neuron e. Source data are provided as a Source Data Fig. 1.