Table 5.
Group | Target Human U87ΔEGFR Glioma Cells (2 × 105) | Target CPA (mg/kg) | Target rQNestin34.5v.2 (PFU) | Total No. of Mice | Target No. of Animals at Each Necropsy |
||
---|---|---|---|---|---|---|---|
Day 4 (M/F) | Day 31 (M/F) | Day 61 (M/F) | |||||
1 | 0 | 0 | 0a | 36 | 6/6 | 6/6 | 6/6 |
2 | 0 | 300 | 0a | 36 | 6/6 | 6/6 | 6/6 |
3 | 0 | 0 | 4.2 × 104 | 36 | 6/6 | 6/6 | 6/6 |
4 | 0 | 300 | 3 × 103 | 36 | 6/6 | 6/6 | 6/6 |
5 | L | 0 | 0a | 30 | 0/10 | 0/10 | 0/10 |
6 | L | 0 | 3.5 × 107 | 41 | 0/10 | 0/10 | 0/10 |
7 | L | 300 | 3.5 × 107 | 35 | 0/10 | 0/10 | 0/10 |
M, male; F, female.
Dulbecco’s phosphate-buffered saline.