Effects of KRG on wrinkle depth and formation in HRM-2 mice. (A) A significant reduction was found in the depth of wrinkles in Weeks 3, 4, and 5 of KRG treatment. The values in bar graphs are the mean ± SEM from three independent experiments. ***p < 0.001, **p < 0.05, and *p < 0.01 compared with the control UVB-irradiated groups. (B) Wrinkle formation in Week 3, 4, and 5 of KRG treatment. HRM-2 N = normal mice, UVB-C= HRM-2 mice control (exposed to UVB), SB = 0.01% sunblock, and K= KRG.
KRG, Korean Red Ginseng; UVB, ultraviolet B.