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. 2020 Apr 23;2020:2603873. doi: 10.1155/2020/2603873

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Copyright © 2020 Xi Zheng and Dong Wang.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of the adenosine A2A receptor agonist on Treg cells and Th17 cells in the blood of fracture rats. Flow cytometry showed that the adenosine A2A receptor agonist could reduce the proportion of Th17 cells in the blood of all CD4+ cells and increase the proportion of Treg cells in the blood of all CD4+ cells in the blood of rats at 1, 2, and 4 weeks after modeling. The adenosine A2A receptor inhibitor can increase the proportion of Th17 cells in the blood of all CD4+ cells and decrease the proportion of Treg cells in the blood of all CD4+ cells. The difference was statistically significant (^∗p < 0.05).