Table 1.
Participant demographics and clinical data
| Continuous Variables | Mean | SD |
|---|---|---|
| Age | 61.8 | 11.5 |
| Disease duration in months | 23 | 20 |
| Disease severity | ||
| • D50 | 36.0 | 24.0 |
| • ALSFRS-R total | 34.8 | 8.6 |
| • ALSFRS-R bulbar (1–3) | 8.6 | 3.4 |
| • ALSFRS-R cervical (4–6) | 6.8 | 3.7 |
| • ALSFRS-R lumbar (7–9) | 6.5 | 3.7 |
| • ALSFRS-R thoracic (10–12) | 9.8 | 2.5 |
| Health-related Quality of Life | ||
| • ALSAQ-40 | ||
| • ALSAQ-40 Mobility | 40.3 | 30.1 |
| • ALSAQ-40 Activities of daily living | 44.0 | 31.6 |
| • ALSAQ-40 Eating | 24.4 | 29.6 |
| • ALSAQ-40 Communication | 43.2 | 36.2 |
| • ALSAQ-40 Emotional well-being | 34.6 | 23.1 |
| Categorical Variables | n | % |
| Male | 95 | 59 |
| Female | 66 | 41 |
| Limb onset | 104 | 64.6 |
| Bulbar onset | 57 | 35.4 |
| rD50-derived Disease Phase | ||
| I | 54 | 33.5 |
| II | 89 | 55.3 |
| III/IV | 18 | 11.2 |