Table 2.
Number of studies selected for each clinical question and study design (literature retrieved from 03/06/2012 to 04/08/2016)
| Clinical questions | RCT a | Observational studies a | Systematic review a |
|---|---|---|---|
| Q1 Pre-assessment and fasting | 1 | 2 | – |
| Q2 Pharmacological Treatment | 15 | 30 | 5 |
| - Midazolam | 3 | 4 | 2 |
| - Fentanyl | 1 | 5 | 1 |
| - Nitrous Oxyde | 1 | 5 | 3 |
| - Ketamine | 12 | 12 | 2 |
| - Propofol | – | 7 | 2 |
| - Dexmedetomidine | 1 | 4 | 2 |
| Q3 Monitoring | 1 | 2 | – |
| Q4 Check List | – | – | – |
| Q5 Training | 1 | 4 | – |
| Q6 Psychological strategies and non-pharmacologic techniques | No systematic search | ||
| Q7 Emergency Medicine Physicians | No systematic search | ||
| Q8 Impact on Organization and Hospital Admissions | No systematic search | ||
a the studies included could report on pooled/summary data on more than one medication