Table 6.
Determination of the levels of TNF-alpha, IL-6 and IL-10 cytokines
| Vehicle control | FO (200 mg/Kg) |
ARF (60 mg/Kg) |
Sty (30 mg/Kg) |
San (30 mg/Kg) |
Nio 1 | Nio 2 | Nio 3 | Nio 4 | Nio 5 | Nio 6 | Placebo I | Placebo II | Ib 100 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TNF-alpha | 2024.60 ± 102.40 | 480.90 ± 28.44* | 343.90 ± 39.33* | 1474.22 ± 10.22* | 1388.12 ± 22.11* | 1560.40 ± 40.98* | 122.55 ± 5.54* | 288.53 ± 10.65* | 1780.22 ± 40.98* | 527.70 ± 33.54* | 704.33 ± 37.44* | 2036.40 ± 122.60 | 2029.12 ± 166.87 | 533.5 ± 96.03 |
| IL-6 | 1212.11 ± 84.00 | 438.25 ± 32.70* | 338.88 ± 28.90* | 1426.10 ± 22.50* | 1378.44 ± 24.30* | 1489.48 ± 39.70* | 111.12 ± 8.55* | 254.33 ± 16.55* | 1370.48 ± 39.66* | 607.23 ± 23.70* | 798.12 ± 43.60* | 1236.33 ± 174.55 | 1208.99 ± 155.65 | 91.18 ± 29.36 |
| IL-10 | 1672.24 ± 60.11 | 3099.34 ± 150.44* | 4636.64 ± 366.43* | 1805.00 ± 18.56* | 1795.33 ± 17.99* | 1750.11 ± 11.74* | 5022.12 ± 125.33* | 4860.22 ± 228.23* | 1740.43 ± 13.77* | 2055.88 ± 100.43* | 1988.88 ± 111.22* | 1588.54 ± 204.68 | 1599.45 ± 258.32 | 114.05 ± 31.44 |
The results are expressed as pg/mg of protein and reported as the mean ± SEM. * p < 0.05