Fig. 7.

Decreased Prdx1 down-regulated the cilium disaggregation signal axis NEDD9-Aurora A-HDAC6 in tumor tissue. a Western-blot was used to detect changes of Prdx1, NEDD9, p-Aurora A, Aurora A, HDAC6, and GAPDH in tumor tissue of each group. b Analysis of western blot signals using Image J. GAPDH was used as a loading control. The relative protein levels are indicated as bars. Full-length blots/gels are presented in Supplementary Fig. X. All experiments were performed in triplicate and results are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001