TABLE 3.
BT vs CG main effects on PAG-dependent rs-FC at T2
| MNI coordinates | ||||||
|---|---|---|---|---|---|---|
| Brain region | Side | x | y | z | Number of voxels | Z score |
| BT > CG | ||||||
| Hypothalamusa | R/L | −8 | −2 | −12 | 5 | 2.01 |
| BT < CG | ||||||
| Anterior cingulate cortex, dorsal | R/L | 2 | 32 | 2 | 198 | 4.48 |
| Anterior cingulate cortex, ventral | L | −12 | 42 | −10 | 89 | 3.82 |
Abbreviations: BT, buprenorphine treatment for opioid use disorder; CG, comparison group; PAG, periaqueductal gray; rs-FC, resting-state functional connectivity.
a
Except this a priori region of interest, all regions listed above were cluster-level whole-brain corrected (family-wise error correction < .05) at voxel-wise P = .001.