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. 2020 May 1;2020(5):CD008649. doi: 10.1002/14651858.CD008649.pub4

6. Jaques 2008 ‐ lung function data (change from baseline at 2 weeks).

Measure Mannitol 
(n = 36) Control 
(n = 36) P Value
Mean SD Mean SD
FEV1 (mL) 121 198 2 198 0.01
FEV1 (% predicted) 3.86 6.48 ‐0.09 6.48 <0.01
FVC (mL) 110 240 40 240 0.16
FEF25-75 (mL/s) 150 300 ‐10 300 0.03

FEF25-75: mid‐expiratory flow; FEV1: forced expiratory volume at one second; FVC: forced vital capacity; mL: millilitres; mL/s: millilitres per second; SD: standard deviation.

Based on additional data provided by Pharmaxis and the primary publication (Jaques 2008).
P value for difference in means taken from F test of Least Squares Generalised mixed model (analysis of variance), see Jaques 2008 for further details.