Table 3.
DHT downregulation of immune-related gene expression in HMGECs
| Accession # | Gene | Ratio | p value | Ontology |
|---|---|---|---|---|
| NM_004591 | Chemokine (C-C motif) ligand 20 | 2.05 | 0.0042 | chemotaxis |
| NM_002993 | Chemokine (C-X-C motif) ligand 6 | 1.99 | 0.0367 | chemotaxis |
| NM_001511 | Chemokine (C-X-C motif) ligand 1 | 1.99 | 0.0028 | chemotaxis |
| NM_000584 | Interleukin 8 | 1.93 | 0.0019 | angiogenesis |
| NM_001565 | Chemokine (C-X-C motif) ligand 10 | 1.67 | 0.0013 | chemotaxis |
| NM_002994 | Chemokine (C-X-C motif) ligand 5 | 1.61 | 0.0002 | chemotaxis |
| NM_002994 | Chemokine (C-X-C motif) ligand 5 | 1.54 | 0.0159 | chemotaxis |
| NM_022873 | Interferon, alpha-inducible protein 6 | 1.39 | 0.0049 | immune response |
| NM_006290 | Tumor necrosis factor, alpha-induced protein 3 | 1.39 | 0.0304 | B-1 B cell homeostasis |
| NM_000576 | Interleukin 1, beta | 1.33 | 0.0017 | chronic inflammatory response to antigenic stimulus |
| NM_006332 | Interferon, gamma-inducible protein 30 | 1.29 | 0.0293 | cytokine-mediated signaling pathway |
| AB074172 | Interleukin 6 signal transducer | 1.29 | 0.0060 | positive regulation of acute inflammatory response |
| NM_006147 | Interferon regulatory factor 6 | 1.28 | 0.0065 | cytokine-mediated signaling pathway |
| NM_021649 | Toll-like receptor adaptor molecule 2 | 1.28 | 0.0074 | toll-like receptor signaling pathway |
| NM_001004196 | CD200 molecule | 1.27 | 0.0246 | regulation of immune response |
| NM_138806 | CD200 receptor 1 | 1.26 | 0.0239 | regulation of immune response |
| NM_003921 | B-cell CLL/lymphoma 10 | 1.26 | 0.0112 | toll-like receptor signaling pathway |
| NM_003238 | Transforming growth factor, β2 | 1.25 | 0.0109 | immune effector process |
| NM_002089 | Chemokine (C-X-C motif) ligand 2 | 1.19 | 0.0425 | chemotaxis |
| NM_022059 | Chemokine (C-X-C motif) ligand 16 | 1.13 | 0.0199 | chemotaxis |
| NM_004048 | Beta-2-microglobulin | 1.1 | 0.0073 | positive regulation of T cell mediated cytotoxicity |
| NM_002198 | Interferon regulatory factor 1 | 1.09 | 0.0206 | cytokine-mediated signaling pathway |
Accession numbers are the sequence identities of gene fragments expressed on the Illumina BeadChips. These sequences are listed in the nucleotide database of the National Center for Biotechnology Information (NCBI). Relative ratios were calculated by comparing the degree of gene expression in HMGECs after vehicle and DHT treatment. Ratios were determined by using non-transformed data.