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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Natl Compr Canc Netw. 2019 Jul 1;17(7):795–803. doi: 10.6004/jnccn.2018.7274

Table 2.

Changes in PSA (Exposure) and Cholesterol (Control) Testing, By Policy Period, 2008–2016

Eligible No. PSA Screening (Exposure), % Cholesterol Screening (Control), % Adjusted Difference-in-Differences Estimate (95% CI), Percentage Points
Age Group Pre-policy (Control; Exposed) Post-policy (Control; Exposed) Pre-policy Post-policy Unadjusted Difference (95% CI), Percentage Points Pre-policy Post-policy Unadjusted Difference (95% CI), Percentage Points
Tertiary Academic Medical Center
All Men 18,559 78,281 17.8 10.7 −7.1 30.6 31.3 0.7 −8
18,303 77,407 (−7.7 to −6.5) (0.0 to 1.4) (−8.9 to −7.1)
35–54 9,574 36,517 13.6 5.3 −8.3 32 28.1 −3.9 −4.8
9,566 36,484 (−9.0 to −7.6) (−4.9 to −2.9) (−6.0 to −3.7)
55–74 6,556 32,756 26.5 17.1 −9.4 31.6 35.2 3.6 −13
6,389 32,256 (−10.6 to −8.2) (2.4 to 4.8) (−14.7 to −11.4)
75+ 2,429 9,008 10.8 9.8 −1 22.6 29.9 7.3 −8.5
2,348 8,667 (−2.4 to 0.4) (5.4 to 9.2) (−11.0 to −6.1)
Optum 1% Sample
All Men 93,334 110,067 9.6 15.4 5.8 18.6 28 9.4 −3.6
(5.5 to 6.1) (9.0 to 9.8) (−4.1 to −3.2)
35–54 49,571 46,359 7.6 10.7 3.1 18.3 25.6 7.3 −4.1
(2.7 to 3.5) (6.8 to 7.8) (−4.8 to −3.5)
55–74 35,148 48,215 12.9 20.5 7.6 20.2 30.7 10.5 −2.8
(7.1 to 8.1) (9.9 to 11.1) (−3.6 to −2.0)
75+ 8,615 15,493 8.2 13.5 5.3 13.1 26.7 13.6 −8.2
(4.5 to 6.1) (12.6 to 14.6) (−9.6 to −6.9)

Notes: All comparisons are between the pre-policy (2008–2011) and post-policy (2013–2016) periods in primary care. Time intervals were defined as calendar years and evaluated independently for patient-level eligibility. Adjusted difference-in-differences estimates are corrected for age, Charlson comorbidity, race, and insurance provider type for the academic center, while the Optum sample is corrected for age, race, and socioeconomic status (net worth). Charlson comorbidity and age were derived on an annual basis. CI, confidence interval. All p-values <0.001.