Table 3.

Changes in Proportion of Early Stage Diagnoses for Prostate Cancer (Exposure) Compared to Colorectal Cancer (Controls) at an Academic Medical Center and in the SEER Registry, By Age Group, 2008–2016.

	Prostate Cancer					Colorectal Cancer
	Pre-policy		Post-policy			Pre-policy		Post-policy
Age Group	Total Diagnosed	No. Early Stage (%)	Total Diagnosed	No. Early Stage (%)	Difference, (95% CI)	Total Diagnosed	No. Early Stage (%)	Total Diagnosed	No. Early Stage (%)	Difference, (95% CI)
Academic Medical Center
All Men	2,572	2,032 (79.0)	1,397	885 (63.4)	−15.6	413	198 (47.9)	521	279 (53.6)	5.6a
					(−18.6, −12.7)					(−0.8, 12.1)
35–54	332	267 (80.4)	143	93 (65.0)	−15.4	122	48 (39.3)	168	73 (43.5)	4.1a
					(−24.3, −6.5)					(−7.4, 15.6)
55–74	1,895	1,488 (78.5)	1,095	691 (63.1)	−15.4	203	94 (46.3)	266	156 (58.6)	12.3
					(−18.8, −12.0)					(3.3, 21.4)
75+	345	277 (80.3)	159	101 (63.5)	−16.8	88	56 (63.6)	87	50 (57.5)	−6.2a
					(−25.3, −8.2)					(−20.6, 8.3)
SEER
All Men	75,641	62,469 (82.6)	44,904	34,875 (77.7)	−4.9	20,250	8,915 (44.0)	15,077	6,286 (41.7)	−2.3
					(−5.4, −4.4)					(−3.4, −1.3)
35–54	8,587	6,901 (80.4)	4,476	3,481 (77.8)	−2.6	4,841	2,062 (42.6)	3,802	1,576 (41.5)	−1.1a
					(−4.1, −1.1)					(−3.2, 1.0)
55–74	53,875	44,525 (82.6)	33,256	26,110 (78.5)	−4.1	10,437	4,661 (44.7)	8,067	3,423 (42.4)	−2.2
					(−4.7, −3.6)					(−3.7, −0.8)
75+	13,179	11,043 (83.8)	7,172	5,284 (73.7)	−10.1	4,972	2,192 (44.1)	3,208	1,287 (40.1)	−4
					(−11.3, −8.9)					(−6.2, −1.8)

Notes: All comparisons are between the pre-policy (2008–2011) and post-policy (2013–2016) periods. Time intervals were defined as calendar years and evaluated independently for patient-level eligibility. Differences are unadjusted and evaluated by Chi square test. CI, confidence interval.

^*p-value - <0.0001 unless otherwise specified;

^ap-value >0.05