Table 2. Results of univariate logistic regression analysis model for probability of unfavorable outcome (mRS score ≥2) among thrombolysed patients.
| Characteristics | mRS score ≥ 2 ( N = 14) | mRS score < 2 ( N = 46) | OR (95%CI) | p -Value |
|---|---|---|---|---|
| Abbreviations: AF, atrial fibrillation; ASPECT, Alberta Stroke Program Early CT score; BMI, body mass index; CBG, capillary blood glucose; CHADS2, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke [double weight]; CI, confidence interval; EF, ejection fraction; LS, lacunar stroke; MABP, mean arterial blood pressure; mRS, modified Rankin scale; NIHSS, National Institute of Health Stroke Scale; OR, odds ratio; PACS, partial anterior circulation stroke; PCS, posterior circulation stroke; ref., reference; SD, standard deviation; TACS, total anterior circulation stroke; TIA, transient ischemic attack. | ||||
| Female sex ( N = 26) | 7 | 19 | 1.4 (0.42–4.72) | 0.39 |
| BMI | 26.6 ± 1.6 | 26.3 ± 0.67 | 0.30 | |
| Bottom tertile (ref.) | 25.8–26.33, N = 5 | 25.3–25.9, N = 20 | ||
| Middle tertile | 26.34–26.86, N = 4 | 26–26.6, N = 12 | 1.33 (0.29–5.95) | 0.4 |
| Upper tertile | 26.87–27.40, N = 5 | 26.7–27.3, N = 14 | 1.42 (0.34–5.88) | 0.72 |
| Age | 69.6 ± 2.06 | 62.11 ± 10.01 | 0.0076 | |
| Bottom tertile (ref.) | 66.5–68.5, N = 2 | 52.1–58.77, N = 21 | ||
| Middle tertile | 68.6–70.6, N = 4 | 58.78–65.45, N = 15 | 2.8 (0.45–17.31) | 0.38 |
| Upper tertile | 70.7–72.7, N = 8 | 65.46–72.13, N = 10 | 8.4 (1.49–47.04) | 0.01 |
| Hypertension ( N = 44) | 10 | 34 | 0.88 (0.23–3.34) | 1.0 |
| Hypercholesterolemia ( N = 36) | 11 | 25 | 1.9 (0.52–7.04) | 0.36 |
| Diabetes ( N = 27) | 10 | 17 | 4.2 (1.15–15.72) | 0.03 |
| Previous TIA ( N = 9) | 5 | 4 | 5.83 (1.3–26.11) | 0.025 |
| Current smoking ( N = 15) | 4 | 11 | 1.27 (0.33–4.8) | 0.99 |
| Ischemic heart disease ( N = 7) | 3 | 4 | 2.86 (0.55–14.72) | 0.33 |
| AF ( N = 6) | 4 | 2 | 8.4 (1.3–52.47) | 0.02 |
| Low EF (<35%) ( N = 7) | 5 | 2 | 11.66 (1.9–69.94) | 0.006 |
| CHADS2 score ≥2 ( N = 24) | 11 | 13 | 9.3 (2.22–38.85) | 0.0013 |
| TACS ( N = 11) | 8 | 3 | 19.11 (3.9–92.6) | 0.0001 |
| PACS ( N = 13) | 4 | 9 | 1.6 (0.4–6.46) | 0.71 |
| PCS ( N = 14) | 2 | 12 | 0.47(0.09–2.4) | 0.48 |
| LS ( N = 22) | 0 | 22 | 0 | 0.0009 |
| Patients thrombolysed between 3 and 4.5 h ( N = 36) | 9 | 27 | 1.26 (0.36–4.38) | 0.76 |
| NIHSS | 16.82 ± 4.82 | 11.4 ± 3.4 | 0.0001 | |
| Bottom tertile (ref.) | 12.0–15.21, N = 2 | 8.0–10.2, N = 21 | ||
| Middle tertile | 15.22–18.43, N = 4 | 10.3–12.5, N = 15 | 2.8 (0.45–17.31) | 0.3 |
| Upper tertile | 18.44–21.65, N = 8 | 12.6–14.8, N = 10 | 8.4 (1.49–47.04) | 0.01 |
| MABP | 118.20 ± 5.2 | 105.85 ± 9.35 | 0.0001 | |
| Bottom tertile (ref.) | 112.9–116.43, N = 2 | 96.5–102.7, N = 21 | ||
| Middle tertile | 116.44–119.97, N = 5 | 102.7–108.9, N = 13 | 3.43 (0.59–20.01) | 0.22 |
| Upper tertile | 119.98–123.51, N = 7 | 109–115.2, N = 12 | 6.41 (1.14–35.89) | 0.03 |
| CBG | 170.5 ± 11.0 | 163.6 ± 9.7 | 0.0276 | |
| Bottom tertile (ref.) | 159.5–166.8, N = 3 | 153.9–160.3, N = 24 | ||
| Middle tertile | 166.9–174.2, N = 4 | 160.4–166.8, N = 12 | 2.66 (0.51–13.87) | 0.3 |
| Upper tertile | 174.2–181.5, N = 7 | 166.9–173.3, N = 10 | 5.6 (1.19–26.13) | 0.03 |
| Fibrinogen | 460.2 ± 12.2 | 452.8 ± 6.7 | 0.0048 | |
| Bottom tertile (ref.) | 447.8–455.9, N = 2 | 446.1–450.56, N = 18 | ||
| Middle tertile | 455.9–464.0, N = 5 | 450.57–455.02, N = 20 | 2.5(0.42–14.60) | 0.42 |
| Upper tertile | 464.0–472.1, N = 7 | 455.03–459.48, N = 8 | 7.87 (1.33–46.62) | 0.02 |