Table 3. Results of univariate logistic regression analysis model for probability of mortality among thrombolysed patients.
| Characteristics | Mortality ( N = 4) | Surviving ( N = 56) |
OR (95%CI) | p -Value |
|---|---|---|---|---|
| Abbreviations: AF, atrial fibrillation; BMI, body mass index; CBG, capillary blood glucose; CI, confidence interval; CHADS2, congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke [double weight]; EF, ejection fraction; LS, lacunar stroke; MABP, mean arterial blood pressure; NIHSS, National Institute of Health Stroke Scale; OR, odds ratio; PACS, partial anterior circulation stroke; PCS, posterior circulation stroke; ref., reference; SD, standard deviation; TACS, total anterior circulation stroke; TIA, transient ischemic attack. | ||||
| Female sex ( N = 26) | 2 | 24 | 1.09 (0.14–8.42) | 1.0 |
| BMI | 26.45 ± 0.85 | 25.80 ± 0.80 | 0.12 | |
| Bottom tertile (ref.) | 25.5–26.1, N = 1 | 25.0–25.53, N = 20 | ||
| Middle tertile | 26.1–26.7, N = 1 | 25.54–26.07, N = 18 | 1.11 (0.06–19.09) | 1.0 |
| Upper tertile | 26.8–27.4, N = 2 | 26.08–26.60, N = 18 | 2.22 (0.18–26.62) | 0.6 |
| Age | 68.51 ± 4.01 | 62.8 ± 10.6 | 0.29 | |
| Bottom tertile (ref.) | 64.5–67.17, N = 1 | 52.2–59.2, N = 21 | ||
| Middle tertile | 67.18–69.85, N = 2 | 59.3–66.3, N = 23 | 1.82(0.15–21.63) | 1.0 |
| Upper tertile | 69.86–72.53, N = 1 | 66.4–73.4, N = 12 | 1.75 (0.1–30.59) | 1.0 |
| Hypertension ( N = 44) | 3 | 41 | 0.36 (0.03–4.22) | 0.41 |
| Hypercholesterolemia ( N = 36) | 3 | 33 | 1.18 (0.11–12.42) | 1 |
| Diabetes ( N = 27) | 2 | 25 | 0.84 (0.1–6.48) | 1.0 |
| Previous TIA ( N = 9) | 2 | 7 | 5.57 (0.66–46.38) | 0.14 |
| Current smoking ( N = 15) | 1 | 14 | 0.76 (0.07–7.9) | 1.0 |
| Ischemic heart disease ( N = 7) | 2 | 5 | 8.2 (0.93–71.7) | 0.08 |
| AF ( N = 6) | 2 | 4 | 10.5 (1.14–95.9) | 0.06 |
| Low EF (<35%) ( N = 7) | 2 | 5 | 10.5 (1.14–95.9) | 0.06 |
| CHADS2 score≥2 ( N = 24) | 4 | 20 | Infinity | 0.04 |
| TACS ( N = 11) | 2 | 9 | 4.11 (0.5–33.27) | 0.20 |
| PACS ( N = 13) | 1 | 12 | 8.5 (0.8–89.74) | 0.07 |
| PCS ( N = 14) | 1 | 13 | 0.84 (0.08–8.89) | 1 |
| LS ( N = 22) | 0 | 22 | 0 | 0.12 |
| Patients thrombolysed between 3 and 4.5 h ( N = 36) | 2 | 34 | 0.35 (0.04–2.74) | 0.56 |
| MABP | 116.2 ±7.3 | 105.6 ± 9.2 | 0.028 | |
| Bottom tertile (ref.) | 108.9–114.1, N = 0 | 96.4–102.53, N = 29 | ||
| Middle tertile | 114.2–119.3, N = 1 | 102.54–108.67, N = 21 | Infinity | 0.43 |
| Upper tertile | 119.4–124.6, N = 2 | 108.68–114.81, N = 6 | Infinity | 0.04 |
| CBG | 171.9± 11.0 | 161.2 ± 8.2 | 0.016 | |
| Bottom tertile (ref.) | 160.9–168.2, N = 1 | 153–158.47, N = 29 | ||
| Middle tertile | 168.3–176.5, N = 0 | 158.48–163.95, N = 16 | 0 | 1 |
| Upper tertile | 176.6–183.9, N = 2 | 163.96–169.43, N = 11 | 20 (1.4–272.33) | 0.03 |
| NIHSS | 16.95 ± 5.05 | 12.7 ± 3.6 | 0.02 | |
| Bottom tertile (ref.) | 11.9–15.2, N = 0 | 8.1–11.1, N = 24 | ||
| Middle tertile | 15.3–18.6, N = 0 | 11.2–14.2, N = 20 | – | 1 |
| Upper tertile | 18.7–22.4, N = 4 | 14.3–17.3, N = 12 | Infinity | 0.02 |
| Fibrinogen | 472.2 ± 8.6 | 450.7 ± 11.5 | 0.0006 | |
| Bottom tertile (ref.) | 463.6–469.3, N = 0 | 462.2–469.8, N = 23 | ||
| Middle tertile | 469.4–475.1, N = 1 | 469.9–477.5, N = 23 | Infinity | 1 |
| Upper tertile | 475.2–480.9, N = 3 | 477.6–485.2, N = 10 | Infinity | 0.04 |