Table 1.
Distribution of baseline characteristics stratified by analgesic use in the first menstrual cycle of observation among women in the Time to Conceive cohort, 2008–2016 (N=858 a).
| Medication use in the first observed cycle | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Overall | Acetaminophen | Aspirin | NSAID | None | ||||||
| N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | |
| 150 | 17 | 10 | 1 | 33 | 4 | 684 | 78 | |||
| Age (years) | ||||||||||
| 29 – 30 | 176 | (21) | 28 | (19) | 2 | (20) | 5 | (15) | 141 | (21) |
| 31 – 32 | 262 | (31) | 46 | (31) | 3 | (30) | 13 | (39) | 200 | (30) |
| 33 – 35 | 233 | (27) | 43 | (29) | 1 | (10) | 7 | (21) | 182 | (27) |
| 36 – 40 | 160 | (19) | 25 | (17) | 1 | (10) | 8 | (24) | 126 | (19) |
| >40 | 27 | (3) | 5 | (3) | 3 | (30) | 0 | 0 | 19 | (3) |
| Race | ||||||||||
| African-American | 79 | (9) | 7 | (5) | 1 | (10) | 0 | 0 | 71 | (11) |
| Caucasian | 664 | (77) | 132 | (90) | 7 | (70) | 29 | (88) | 496 | (74) |
| Other | 115 | (13) | 8 | (5) | 2 | (20) | 4 | (12) | 101 | (15) |
| Education | ||||||||||
| Some college or less | 62 | (7) | 8 | (5) | 0 | 0 | 3 | (9) | 51 | (8) |
| College graduate | 164 | (19) | 24 | (16) | 2 | (20) | 6 | (18) | 132 | (20) |
| Some graduate school or Master’s degree | 413 | (48) | 81 | (55) | 4 | (40) | 17 | (52) | 311 | (47) |
| Doctoral degree (MD, PhD) | 219 | (26) | 34 | (23) | 4 | (40) | 7 | (21) | 174 | (26) |
| Body mass index (kg/m3) | ||||||||||
| <20 | 103 | (12) | 15 | (10) | 1 | (10) | 3 | (9) | 84 | (13) |
| 20 – 25 | 454 | (53) | 84 | (57) | 5 | (50) | 17 | (52) | 348 | (52) |
| >25 – 30 | 174 | (20) | 26 | (18) | 3 | (30) | 10 | (30) | 135 | (20) |
| >30 | 126 | (15) | 21 | (14) | 1 | (10) | 3 | (9) | 101 | (15) |
| Nulligravid | ||||||||||
| No | 424 | (49) | 62 | (42) | 7 | (70) | 16 | (48) | 339 | (51) |
| Yes | 434 | (51) | 85 | (58) | 3 | (30) | 17 | (52) | 329 | (49) |
| Frequency of intercourse in the fertile window (days) | ||||||||||
| 0 | 314 | (37) | 28 | (19) | 2 | (20) | 7 | (21) | 277 | (41) |
| 1 | 96 | (11) | 27 | (18) | 0 | 0 | 7 | (21) | 62 | (9) |
| 2 | 172 | (20) | 36 | (24) | 2 | (20) | 7 | (21) | 127 | (19) |
| 3 | 143 | (17) | 28 | (19) | 3 | (30) | 6 | (18) | 106 | (16) |
| 4 | 70 | (8) | 14 | (10) | 1 | (10) | 5 | (15) | 50 | (7) |
| 5 or 6 | 63 | (7) | 14 | (10) | 2 | (20) | 1 | (3) | 46 | (7) |
| Alcoholic drinks per month | ||||||||||
| 0 – 1 | 308 | (36) | 41 | (28) | 4 | (40) | 10 | (30) | 253 | (38) |
| 2 – 8 | 274 | (32) | 54 | (37) | 2 | (20) | 9 | (27) | 209 | (31) |
| 9 – 60 | 273 | (32) | 50 | (34) | 4 | (40) | 13 | (39) | 206 | (31) |
| Caffeinated drinks per day | ||||||||||
| 0 | 141 | (16) | 15 | (10) | 2 | (20) | 4 | (12) | 120 | (18) |
| 1 | 409 | (48) | 66 | (45) | 4 | (40) | 13 | (39) | 326 | (49) |
| 2 | 235 | (27) | 47 | (32) | 2 | (20) | 12 | (36) | 174 | (26) |
| >2 | 72 | (8) | 19 | (13) | 2 | (20) | 3 | (9) | 48 | (7) |
| History of migraines | ||||||||||
| Yes | 220 | (26) | 54 | (37) | 3 | (30) | 9 | (27) | 154 | (23) |
| No | 638 | (74) | 93 | (63) | 7 | (70) | 24 | (73) | 514 | (77) |
| History of fibroids | ||||||||||
| Yes | 31 | (4) | 4 | (3) | 1 | (10) | 1 | (3) | 25 | (4) |
| No | 827 | (96) | 143 | (97) | 9 | (90) | 32 | (97) | 643 | (96) |
a
Variables that don’t sum to 858 are due to missing values.
NSAID: Nonsteroidal anti-inflammatory drug