. Author manuscript; available in PMC: 2021 May 1.

Published in final edited form as: Am J Obstet Gynecol. 2019 Nov 20;222(5):493.e1–493.e13. doi: 10.1016/j.ajog.2019.11.1252

Table 3.

Proteins expressed at significantly different levels in CVF samples from spontaneous preterm birth cases and term delivery controls.

Protein	Peptides	Fold Change	+/−	P
Second Study Visit (19^0/7–23^6/7 wk)
Laminin alpha 3 subunit isoform	2	2.6	+	0.05
Cystatin C precursor	2	2.3	+	0.002
Laminin A/C isoform 2	2	1.8	+	0.05
Calsyntenin 1 isoform 2	1	1.7	+	0.007
Third Study Visit (28^0/7–31^6/7 wk)
Extracellular matrix protein 1 isoform 1 precursor	2	4.7	+	0.02
Tissue inhibitor of metalloproteinase 1 precursor	2	1.7	−	0.05
HSP-beta 1	1	1.9	−	0.04
Calsyntenin 1 isoform 2	1	2.3	−	0.05
Laminin alpha 3 subunit isoform	1	2.2	−	0.04
Urokinase plasminogen activator preprotein	1	2.1	−	0.05
Both Visits
Fibronectin-1	2	1.7	+	0.05
Extracellular matrix protein 1 isoform 1 precursor	2	2.3	+	0.02
Laminin alpha 3 subunit isoform	2	2.5	+	0.03
Laminin A/C isoform 2	2	1.7	+	0.04
Desmoplakin isoform 1	1	1.5	−	0.03
Calsyntenin 1 isoform 2	1	1.4	+	0.02

Peptides: number of peptides for each protein demonstrating different L/H (light endogenous peptide area/heavy stable isotope labeled proteome [SILAP] peptide area); +/−: increase/decrease;

P values: determined by two-sample t tests.