Table 5.
Individual molecular functions of the 28 proteins detected by shotgun proteomics at greater levels in spontaneous preterm births for all three study visits.
| # | Protein Name | Protein ID (Accession Number | Molecular function |
|---|---|---|---|
| 1 | Destrin isoform A | gi|5802966|ref|NP_006861.1| | Actin depolymerization |
| 2 | Titin isoform N2-A | gi|291045225|ref|NP_596869.4| | Actin filament binding |
| 3 | Beta-catenin | gi|148227672|ref|NP_001091680.1| | Activator |
| 4 | Protein-glutamine gamma-glutamyltransferase K | gi|4507475|ref|NP_000350.1| | Acyltransferase |
| 5 | Protein S100-A8 | gi|21614544|ref|NP_002955.2| | Anti-microbial |
| 6 | ATP synthase subunit alpha, mitochondrial precursor | gi|50345984|ref|NP_001001937.1| | ATP binding |
| 7 | ATP synthase subunit beta, mitochondrial precursor | gi|32189394|ref|NP_001677.2| | ATP binding |
| 8 | Plastin-3 isoform 1 | gi|209862851|ref|NP_001129497.1| | Calcium binding |
| 9 | Protein S100-A6 | gi|7657532|ref|NP_055439.1| | Calcium-dependent protein binding |
| 10 | Heat shock 60 kDa protein, mitochondrial | gi|41399285|ref|NP_955472.1| | Chaperone |
| 11 | Heat shock-related 70 kDa protein 2 | gi|13676857|ref|NP_068814.2| | Chaperone |
| 12 | Sacsin | gi|163659918|ref|NP_055178.3| | Chaperone binding |
| 13 | Proteasome 26S non-ATPase subunit 2 | gi|25777602|ref|NP_002799.3| | Enzyme regulator |
| 14 | Leukotriene A4 hydrolase | gi|4505029|ref|NP_000886.1| | Epoxide hydrolase |
| 15 | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 2 isoform 2 precursor | gi|209413738|ref|NP_001129243.1| | Glycotransferase |
| 16 | Cytosolic purine 5’-nucleotidase | gi|197276664|ref|NP_001127845.1| | Hydrolase |
| 17 | Exportin-2 | gi|29029559|ref|NP_001307.2| | Importin-alpha export receptor activity |
| 18 | Nicotinate phosphoribosyltransferase | gi|194394158|ref|NP_660202.3| | Nicotinate phosphoribosyltransferase |
| 19 | Thymidine phosphorylase isoform 1 proprotein | gi|166158925|ref|NP_001107228.1| | Nucleotide phosphorylase |
| 20 | Heme oxygenase 1 | gi|4504437|ref|NP_002124.1| | Oxidoreductase |
| 21 | Cytosolic phospholipase A2 delta | gi|116174754|ref|NP_828848.3| | Phospholipase |
| 22 | Protein disulfide-isomerase A3 precursor | gi|21361657|ref|NP_005304.3| | Protein disulfide isomerase |
| 23 | Cellular retinoic acid binding protein 2 | gi|4503029|ref|NP_001869.1| | Retinoid binding |
| 24 | Eukaryotic translation initiation factor 5A-1 isoform A | gi|219555707|ref|NP_001137232.1| | Ribosome binding |
| 25 | Sulfotransferase family cytosolic 2B member 1 isoform B | gi|31563386|ref|NP_814444.1| | Steroid sulfotransferase |
| 26 | Talin 1 | gi|223029410|ref|NP_006280.3| | Structural constituent of cytoskeleton |
| 27 | Plectin isoform 1E | gi|41322908|ref|NP_958781.1| | Structural constituent of muscle |
| 28 | 14-3-3 protein beta/alpha | gi|21328448|ref|NP_647539.1| | Transcription corepressor activity |