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Mean nerve corneal subbasal fiber density in four STZ-treated and three control Thy1-YFP mice. Based on quantitative results from confocal laser scanning microscopy (CLSM) and two-photon microscopy (TPM) (both of which are forms of confocal microscopy) of corneal nerves in vivo, STZ treatment caused significant reductions in corneal nerve fiber density. Reproduced with permission from [23].
