Figure 3.

miR‐187‐5p and miR‐1323 can regulate the biological functions of GCTBSC. A, The two miRNAs had a low expression in tumor tissues shown by qRT‐PCR. B, The relative levels of the two miRNAs after the transfection of the mimics. C, After the transfection of mimics, the EDU assay examined the proliferation of GCTBSC. And, the right picture showed the statistical results. D, Transfection was tested by transwell assay and statistical result showed the significance. E, The cell counting kit‐8 (CCK8) assay showed that the mimics can inhibit the cellular viability. F, The relative levels of the two miRNAs after the inhibitors transfection. G, The EDU assay and statistic results showed that the two inhibitors can prompt the proliferation. H, The transwell assay verified the improvement of translocation. I, The CCK8 showed the change in cellular viability. “NS”, “*”, “**”, “***”, and “****” represented none sense, P < .05, P < .01, P < .001, and P < .0001, respectively. “NC”, “mimics1”, and “mimics2” represented negative control, miR‐187‐5p mimics, and miR‐1323 mimics, respectively. “INC”, “inhibitors1”, and “inhibitors2” represented inhibitors negative control, miR‐187‐5p inhibitors, and miR‐1323 inhibitors, respectively. GCTB, giant cell tumor of bone