Figure 8.

TUNEL assay to detect apoptotic activity in murine lymphoma sections after AAV6‐iCasp9 suicide gene therapy: A, Representative Images of TUNEL stained tumor sections from murine lymphoma sections after suicide gene therapy is shown. Nuclei stained in red color indicates the TUNEL positive apoptotic cells. Cell nucleus was counter stained by DAPI. B, The number of apoptotic cells were higher in tumors harvested from animals that received vectors generated by the quadruple transfection method. ns, not significant, **P < .01, ***P < .001 vs mock‐treated group