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. 2019 Dec 9;36(2):165–178. doi: 10.1007/s10565-019-09504-5

Fig. 5.

Fig. 5

Effects of 2D-Exos and 3D-Exos on matrix synthesis and the phenotypic stability of chondrocytes. a The protein and mRNA level of genes associated with matrix synthesis and chondrocytic differentiation (Col II, Aggrecan, Sox 9, MMP 13, ADMST5). b Quantitative analysis of s-GAG (left) and s-GAG/DNA (right) when chondrocyte were stimulated by 10 μg/mL exosomes. c Western blot analysis of TGF-β1, P-SMAD2/3, T-SMAD2/3, and Runx 2 of chondrocytes exposed to exosomes. Data represent mean ± SEM. *p < 0.05, **p < 0.01, n = 3