Table 2.
PROM scores of 96 BRCA1/2 mutation carriers per type of cancer risk management, mean (95% CI)
| All (n = 96) | Surveillance (n = 49) | BPM-IBR (n = 47) | p value¥ | |
|---|---|---|---|---|
| Mean (95% CI) | Mean (95% CI) | Mean (95% CI) | ||
| HADS° | ||||
| Anxiety scale | 5.36 (4.62–6.09) | 5.47 (4.30–6.63) | 5.26 (4.30–6.21) | 0.691 |
| Depression scale | 2.40 (1.80–3.00) | 2.51 (1.66–3.36) | 2.30 (1.42–3.18) | 0.591 |
| BREAST-Q§ | ||||
| Satisfaction with breasts | 68.96 (65.09–72.82) | 71.51 (65.56–77.47) | 66.51 (61.42–71.60) | 0.304 |
| Psychosocial well-being | 74.08 (70.14–78.01) | 70.78 (65.17–76.38) | 77.23 (71.67–82.80) | 0.143 |
| Physical well-being chest | 79.32 (76.29–82.34) | 81.78 (76.99–86.57) | 76.96 (73.16–80.75) | 0.011 |
| Sexual well-being | 61.53 (57.87–65.20) | 62.82 (57.24–68.41) | 60.30 (55.33–65.27) | 0.644 |
HADS index value: scale from 0–21; BREAST-Q scale from 0 to 100
BPM-IBR bilateral prophylactic mastectomy followed by immediate breast reconstruction, HADS Hospital Anxiety and Depression Scale
°Higher scores represent lower quality
§Higher scores represent higher quality
¥Mann–Whitney U test