Photodynamic therapy (PDT) plays an important role in the treatment of several chorioretinal diseases, such as central serous chorioretinopathy, polypoidal choroidal vasculopathy, and choroidal hemangioma.

The treatment of choice for chronic central serous chorioretinopathy is PDT with half-dose verteporfin or half-fluence PDT (with full-dose verteporfin).

For the treatment of polypoidal choroidal vasculopathy, PDT with both standard and reduced treatment settings can be considered.

For the treatment of choroidal hemangioma, either standard treatment settings, a bolus protocol, or a high-fluence protocol can be used.

Patients should be adequately informed to avoid direct sunlight after treatment, and side effects during and after PDT are rare.