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. 2020 Apr 24;2020:5298483. doi: 10.1155/2020/5298483

Figure 4.

Figure 4

Effects of melatonin on mitochondrial membrane potential, mitochondrial permeability transition pore (mPTP) opening time, ATP production, and mitochondrial respiratory function in β-GP-treated VSMCs (n = 6/group). (a, b) The change of membrane potential (ΔΨm) by JC-1 staining. (c) Result of arbitrary mPTP opening time. (d) Result of cellular ATP levels. (e–g) Results of mitochondrial respiratory complex (CIII-core2, CII-30, and CIV-II) mRNA expression. (h, i) Results of glucose uptake and lactic acid production. (j, k) Results of mitochondrial State 3/4 respiratory rate. ∗P < 0.05 vs. Con, #P < 0.05 vs. β-GP, and &P < 0.05 vs. β-GP+Mel.