Table 1.
Baseline characteristics of subjects according to the fatty liver index (FLI) quartiles
| Total | FLI (Q1) | FLI (Q2) | FLI (Q3) | FLI (Q4) | |
|---|---|---|---|---|---|
| N | 3,011,588 | 753,155 | 753,007 | 752,868 | 752,528 |
| FLI cutoff value | ≤ 8.49 | 8.5–18.67 | 18.68–37.08 | ≥ 37.09 | |
| Age (years) | 51.86 ± 8.20 | 49.09 ± 7.38 | 52.20 ± 8.02 | 53.35 ± 8.13 | 52.81 ± 8.15 |
| Body mass index (kg/m2) | 23.82 ± 2.91 | 21.05 ± 1.74 | 23.03 ± 1.75 | 24.51 ± 1.92 | 26.69 ± 2.64 |
| Sex (male) | 1,290,580 (42.9%) | 137,010 (18.3%) | 265,501 (35.3%) | 380,022 (50.5%) | 507,975 (67.5%) |
| Systolic blood pressure | 122.26 ± 12.63 | 116.00 ± 11.76 | 121.00 ± 11.99 | 124.33 ± 11.88 | 127.73 ± 11.82 |
| Diastolic blood pressure | 76.20 ± 8.27 | 72.36 ± 7.86 | 75.30 ± 7.86 | 77.37 ± 7.75 | 79.77 ± 7.77 |
| Fasting glucose | 98.10 ± 20.19 | 91.77 ± 12.96 | 95.65 ± 16.81 | 99.37 ± 20.14 | 105.63 ± 25.88 |
| Total cholesterol | 199.61 ± 33.64 | 189.32 ± 30.56 | 198.30 ± 31.92 | 202.87 ± 33.59 | 207.94 ± 35.46 |
| Triglyceride | 111 (80.67, 156) | 72.67 (58.67, 90) | 77.5 (80, 124) | 127 (101,161) | 177 (135.5, 236.5) |
| HDL cholesterol | 55.56 ± 20.92 | 61.72 ± 17.75 | 56.80 ± 18.79 | 53.38 ± 21.00 | 50.32 ± 23.87 |
| LDL cholesterol | 119.49 ± 31.68 | 112.75 ± 28.76 | 121.28 ± 30.31 | 123.59 ± 31.56 | 120.36 ± 34.76 |
| Estimated GFR (mL/min/1.73 m2) | 81.28 ± 23.28 | 74.53 ± 19.87 | 78.34 ± 21.46 | 82.08 ± 22.66 | 90.16 ± 25.80 |
| Income (lower 25%) | 843,511 (28%) | 239,447 (31.8%) | 217,221 (28.9%) | 198,702 (26.4%) | 188,141 (25.0%) |
| Current smoker | 553,254 (18.4%) | 64,933 (8.6%) | 109,309 (14.5%) | 153,046 (20.3%) | 225,966 (30.0%) |
| Regular exercise (%) | 1,668,750 (55.4%) | 403,498 (53.6%) | 420,508 (55.8%) | 424,181 (56.3%) | 420,563 (55.9%) |
| Hypertension (%) | 1,086,672 (36.1%) | 150,088 (19.9%) | 240,205 (31.9%) | 311,619 (41.4%) | 384,760 (51.1%) |
| Diabetes mellitus (%) | 236,874 (7.9%) | 17,827 (2.4%) | 40,090 (5.3%) | 67,422 (9.0%) | 111,535 (14.8%) |
| Use of medication for dyslipidemia (%) | 89,704 (3.0%) | 8,293 (1.1%) | 18,668 (2.5%) | 27,105 (3.6%) | 35,637 (4.7%) |
Data are expressed as the mean ± SD, median (25–75%), or n (%)
FLI fatty liver index, HDL high-density lipoprotein, LDL low-density lipoprotein
*p-values for the trend were < 0.0001 for all variables except regular exercise