Table 1.

Overall patient characteristics of the cohorts

		ADT-naïve(N=1502)		GnRH agonists(N=738)		Antiandrogen only(N=173)		p-value
		N	%	N	%	N	%
Age	Mean, SE	71.1	5.5	74.2	6.1	74.1	6.7	< 0.01
Age group	60-69	655	43.6	190	25.7	49	28.3
	70-79	731	48.7	393	53.3	83	48.0
	80 <	116	7.7	155	21.0	41	23.7
Year of diagnosis of prostate cancer	2003	205	13.6	71	9.6	35	20.2	< 0.01
	2004	245	16.3	89	12.1	28	16.2
	2005	208	13.8	108	14.6	24	13.9
	2006	247	16.4	119	16.1	32	18.5
	2007	280	18.6	162	22.0	25	14.5
	2008	317	21.1	189	25.6	29	16.8
Comorbidity	Diabetes	432	28.8	227	30.8	51	29.5	0.62
	Hypertension	817	54.4	430	58.3	90	52.0	0.14
CCI	Mean, SE	4.2	2.3	4.9	3.0	4.8	2.9	< 0.01
	2	339	22.6	144	19.5	38	22.0
	3	339	22.6	155	21.0	35	20.2
	4	294	19.6	135	18.3	36	20.8
	5<	470	31.3	304	41.2	64	37.0
Comorbidities in CCI	Myocardial infarction	40	2.7	18	2.4	6	3.5	0.75
	Congestive heart failure	75	5.0	57	7.7	15	8.7	0.01
	Peripheral vascular disease	145	9.7	102	13.8	11	6.4	< 0.01
	Cerebrovascular disease	228	15.2	142	19.2	28	16.2	0.05
	Dementia	20	1.3	18	2.4	3	1.7	0.16
	Chronic pulmonary disease	557	37.1	254	34.4	72	41.6	0.17
	Rheumatic disease	74	4.9	38	5.1	6	3.5	0.65
	Peptic ulcer disease	523	34.8	273	37.0	44	25.4	0.02
	Mild liver disease	331	22.0	177	24.0	36	20.8	0.5
	Diabetes without chronic complication	404	26.9	208	28.2	47	27.2	0.81
	Diabetes with chronic complication	136	9.1	76	10.3	13	7.5	0.44
	Hemiplegia or paraplegia	22	1.5	19	2.6	4	2.3	0.17
	Renal disease	35	2.3	23	3.1	5	2.9	0.53
	Moderate or severe liver disease	13	0.9	7	0.9	2	1.2	0.92
	Metastatic solid tumor	81	5.4	107	14.5	29	16.8	< 0.01
	AIDS/HIV	0	0.0	0	0.0	0	0.0	-