Skip to main content
. 2020 Apr 25;11(14):4213–4221. doi: 10.7150/jca.35014

Figure 3.

Figure 3

Down-regulated expression of MTHFD1L reduced the proliferation of colorectal cancer cells. A. Expression of MTHFD1L in CRC cell lines, and the NCM460 cells were used as the normal control. B. The relative expression of MTHFD1L protein in cells, the result was the ratio of MTHFD1L to GAPDH. P<0.05. C, D. Knockdown efficiency of MTHFD1L in DLD-1 and HCT116 cell lines in mRNA and protein level. P<0.05. E, F. MTT assay showed that down-regulating the expression of MTHFD1L could inhibit the proliferation of colorectal cancer cells. P<0.05. G. Down-regulating the expression of MTHFD1L can reduce the clonal formation ability of tumor cells. H. Statistical analysis of the clonal formation ability of low expression MTHFD1L colorectal cancer cells. P<0.05.