Table 5.
Univariate and multivariate analysis of prognostic factors of OS in 200 HCC patients
| Variable | Univariate | Multivariate | ||
|---|---|---|---|---|
| χ2 | p value | HR (95%Cl) | p value | |
| TRIM4 expression (high vs low) | 9.004 | <0.01 | 0.386-0.951 | 0.029 |
| Tumor diameter (cm) (>5 vs ≤5) | 1.338 | 0.247 | - | n.a. |
| Vascular invasion (yes vs no) | 8.596 | <0.01 | 0.916-2.477 | 0.106 |
| Tumor capsule (none vs yes) | 1.866 | 0.172 | - | n.a. |
| Tumor number (≥2 vs 1) | 12.678 | <0.001 | 1.240-3.185 | <0.01 |
| Sex (male vs female) | 0.148 | 0.701 | - | n.a. |
| Age (years) (≤50 vs >50) | 0.722 | 0.395 | - | n.a. |
| AFP (ng/ml) (≤400 vs >400) | 5.018 | 0.025 | 0.699-1.948 | 0.556 |
| Tumor differentiation (III-IV vs I-II) | 0.434 | 0.510 | - | n.a. |
| Liver cirrhosis (positive vs negative) | 4.463 | 0.035 | 0.904-3.633 | 0.094 |
n.a., not applicable.