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. 2020 Apr 27;11(14):4222–4229. doi: 10.7150/jca.38830

Table 1.

Clinicopathological variables and circNFIC expression in 150 breast cancer patients

Characteristics Total (n=150) circNFIC high (n=57) circNFIC low (n=93) P value
No. % No. %
OS 0.002*
Present 104 48 46.2 56 53.8
Absent 46 9 19.6 37 80.4
Age (years) 0.515
<50 66 27 40.9 39 59.1
≥50 84 30 35.7 54 64.3
Tumor size (cm)** 0.473
≤2 34 11 32.4 23 67.6
>2 115 45 39.1 70 60.9
LNMET** 0.021*
Yes 91 28 30.8 63 69.2
No 54 27 50.0 27 50.0
TNM stage** 0.182
I-II 97 40 41.2 57 58.8
III- IV 50 15 30.0 35 70.0
ER status** 0.059
Positive 93 41 44.1 52 55.9
Negative 50 14 28.0 36 72.0
PR status** 0.324
Positive 81 34 42.0 47 58.0
Negative 62 21 33.9 41 66.1
HER-2 status** 0.689
Positive 41 17 41.5 24 58.5
Negative 103 39 37.9 64 62.1

* indicates statistical significance (P < 0.05).

% indicates percentage within the row.

** The case number does not add up to the total in several categories because a few patients were excluded from those categories.