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. 2020 Apr 6;10(12):5195–5208. doi: 10.7150/thno.45017

Figure 3.

Figure 3

Responsiveness, selective cell uptake and cytotoxicity of Au NPs. (A) UV spectra, (B) hydrodynamic diameter and surface zeta potential of as-prepared ultrasmall Au@Tat-R-EK NPs and the ones treated with cathepsin B, respectively. (C) Plot of the gold concentration in LM3 cells as a function of incubation time that cells exposed to ultrasamll Au NPs (20 μg/mL, n=4). (D) Relative viablity of LM3 cells incubated with various concentrations of ultrasmall Au NPs for 24 h, and then treated with X-ray (4 Gy, n=4). * indicates significant difference at P < 0.05 level.