Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 6;10(12):5242–5258. doi: 10.7150/thno.43744

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

CDYL2b inhibits breast cancer cell migration and invasion through transcriptional inhibition of HPSE, HLA-F, and SELL. (A) MDA-MB-231 and Hs578T cells stably expressing pCDH, Flag-CDYL2b, or Flag-CDYL2b were transfected with plasmid DNAs encoding HA-HPSE, HA-HLA-F, or HA-SELL. The expression status of HA-HPSE, HA-HLA-F, or HA-SELL in these cells was validated by immunoblotting with an anti-HA antibody. (B-C) The established cell lines were subjected to Boyden's chamber migration assays and Matrigel-coated invasion assays. Representative images of Transwell migration and invasion assays are shown in B and corresponding quantitative results are shown in C. *, ** and *** are significant differences at p<0.05, p<0.01, and p<0.001 levels, respectively.