Table 5.
Representative Commercial Products Utilizing Physical Transfection
| Physical Methods | Company | Products | Product Type | Technology |
|---|---|---|---|---|
| Mechanical | Indee Labs | Under development | Device | Microfluidic vortex shedding |
| Mechanical | CellFE | Under development | Device | Microfluidic constriction |
| Mechanical | SQZ Biotech | SQZ-PBMC-HPV | Cell therapy | Microfluidic constriction |
| Mechanical & Electrical | OpenCell Technologies | POROS-EP | Device | Combination of acoustic shear poration and electrophoresis |
| Electrical | Lonza | Nucleofector | Device | Conventional electroporation |
| Electrical | Biorad | Gene Pulsar | Device | Conventional electroporation |
| Electrical | ThermoFisher Scientific | Neon Transfection System | Device | Conventional electroporation |
| Electrical | Miltenyi Biotec | CliniMACS® Electroporator | Device | Automated conventional electroporation |
| Electrical | MaxCyte | MaxCyte STX® | Device | Flow electroporation |
| CARMA™ | Cell therapy | |||
| Electrical | Celetrix | CTX Electroporator | Device | Tube electroporation |
| Electrical | Infinitesimal | NFP-E™ | Device | Nanostructure-mediated electroporation |
| Electrical | NAVAN Technologies | Under development | Device | Nanostructure-mediated electroporation |
| Laser/Thermal | Cellino Biotech | Under development | Device | Nanostructure-mediated plasmonic poration |
| Magnetic | OZ Biosciences | Magnetofection™ | Reagent | Magnetic particle-assisted transfection |
| Magnetic | PromoCell | MATra | Reagent | Magnetic particle-assisted transfection |