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. Author manuscript; available in PMC: 2020 Dec 6.
Published in final edited form as: JAMA Ophthalmol. 2019 Aug 1;137(8):939–944. doi: 10.1001/jamaophthalmol.2019.1576

Table.

International Classification of Retinopathy of Prematuritya

Location of Disease Description
Zone I A circle centered on the optic disc with radius twice the distance from the optic disc to the fovea
Zone II The region within a circle centered on the optic disc with radius from the optic disc to the nasal ora serrata, excluding the area within zone I
Zone II The temporal crescent outside of zone II
Staging
 Stage 1 A demarcation line that separates the vascular from avascular retina
 Stage 2 A ridge separates the vascular from avascular retina
 Stage 3 Extraretinal fibrovascular proliferation
 Stage 4a Partial retinal detachment not involving the fovea
 Stage 4b Partial retinal detachment involving the fovea
 Stage 5 Total retinal detachment
a

Data from International Committee for the Classification of Retinopathy of Prematurity.32