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. 2019 Jul;22(7):820–826. doi: 10.22038/ijbms.2019.34609.8211

Table 3.

The effect of pharmacological intervention on post ischemic maximum rate of relaxation (-dp/dtmin) in rat hearts subjected to 30 min global ischemia followed by 120 min reperfusion at different time intervals. All values are represented as absolute values of dp/dtmin in mmHg/sec. Values were represented as mean ± SD (n=6 in each group). For treatment, F (7, 200) =63.9; for time, F (4, 200) =1287; a =P<0.05 vs Basal; b =P<0.05 vs Sham; c =P<0.05 vs RIPC (remote ischemic preconditioning); d =P<0.05 vs SNP (sodium nitroprusside); e =P<0.05 vs morphine

Group Baseline Reperfusion
5 min 30 min 60 min 120 min
Sham 2947±251 1234±129a 1438±15a 1139±132a 952±98a
RIPC 3227±258 1910±195a,b 2061±192a,b 1640±172a,b 1383±15a,b
RIPC+L-NAME 3071±228 1342±158a,c 1479±123a 1176±109a,c 988±87a
SNP 3296±272 2034±216a,b 2249±228a,b 1761±168a,b 1442±166a,b
RIPC+Naloxone 3119±243 1398±125a,c 1505±129a 1196±106a,c 995±95a
Morphine 3340±290 2110±22a,b 2289±205a,b 1812±183a,b 1558±179a,b
SNP+Naloxone 3186±263 1439±143a,d 1687±182a,d 1249±139a,d 965±92a,d
Morphine+
Glibenclamide
3214±259 1562±159a,e 1736±178a,e 1499±145a 1164±125a,e