Table 3.
Prevalence of multi-drug resistance, β-lactamases production and class 1 integron among Pseudomonas aeruginosa from hospitalized patients of four hospitals of Iran
| source/samples | number of isolates | % MDR | ESBL | MBL(in MDRPA) | AmpC |
IMI
mean MIC (µg/ml) (E-test) |
*MBL genes | |
|---|---|---|---|---|---|---|---|---|
| IMP-1 | VIM | |||||||
| burn exudate | 53 | 36(68) | 46(86.8) | 32(89.9) | 18(50) | 64 | 29(80) | 4(11) |
| urine | 48 | 18(37.5) | 32(66.7) | 9(50) | 5(27.7) | 64 | 14(77) | |
| sputum | 29 | 11(38) | 20(69) | 6(54.5) | 1(9.1) | 128 | 10(90) | - |
| blood | 23 | 4(17.4) | 12(52) | 1(25) | - | 32 | 4(100) | - |
| wound | 22 | 6(27.3) | 15(68) | 2(33.3) | 3(50) | 64 | 6(100) | - |
| eye | 14 | 3(21.5) | 6(42.8) | 3(50) | 1(33.3) | 64 | 3(100) | - |
| others | 19 | 6(31.5) | 14(73.7) | 1(16.7) | - | 32 | 5(83) | - |
| total | 208 | 84(40.4) | 145(70) | 54(64.3) | 28(33) | - | 71(84.5) | 4(4.8) |
MDR= multidrug-resistant, MBL= metallo-β-lactamase, ESBL= extended spectrum-β-lactamase, IMI= imipenem, intΙ1= class 1 integrons integrase gene. Value in bracket indicate % in MDR population.*.NDM gene was not detected in any isolate. Others = fluids/c, Nose/c, etc